The U.S. pharmacies and drug stores market is $609.6 billion in 2025 IBISWorld, while total prescription dispensing revenues at retail, mail, long-term care, and specialty pharmacies reached $683 billion in 2024, up 9% from the previous year. Drugchannels The drug store industry continues to see significant consolidation. The largest four companies operating pharmacies—CVS Health, Walgreens Boots Alliance, Cigna, and UnitedHealth Group—accounted for half of total U.S. prescription dispensing revenues in 2024 Drugchannels, while the top 15 companies accounted for about three-quarters of total dispensing revenues. Drugchannels
Over the past four years, the three largest drugstore chains have collectively cut nearly 3,000 locations. Rite Aid has emerged from bankruptcy as a private company, while Walgreens Boots Alliance is attempting an acquisition by Sycamore Partners. Drugchannels In March 2025, Walgreens announced an agreement to be acquired by Sycamore Partners for $23.7 billion Drug Topics, and Rite Aid emerged from Chapter 11 bankruptcy in 2024 as a private company but was reduced to around 1,200 stores. AJMC
NPI has relationships with the largest drug retail chains in the country, including CVS and Walgreens. CVS and Walgreens have a serious advantage over other retail pharmacies since around 70% to 80% of the U.S. population lives within five miles of either drugstore. MedCity News We have the established infrastructure to seamlessly place your brand in a position to capitalize on the opportunities available in this channel.
NPI provides clients with solutions for greater performance in the drug channel using market analytics and strategy. We consistently deliver growth solutions with exceptional service to manufacturers in this channel, with a focus on the leading drug retailers. Contact the NPI team today to learn how we can assist you with the Drug Store retail market.



